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levomenol 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| 4619 | 23089-26-1 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
drug combination containing chamomile and bisabolol; used to treat dermatitis
|
Drug dosage:
None
ADMET properties:
None
Predicted pharmacokinetic/toxicological properties (PK-AZ):
| Property | Description | Value | Unit | Confidence | Similarity |
|---|---|---|---|---|---|
| kinase-safety-class | ACVR2B,AXL,BRAF,CAMK2D,CDK4,CDK5,CDK9,EIF2AK3,EPHB4,ERBB2,GRK2,ITK,MAPK7,NTRK2,PDK2,PDK4,PRKDC,TEK,TGFBR1 | 19 | |||
| kinase-selectivity-class | PDK2 | 1 | |||
| pfas-class | PFAS structural alert (1 = True, 0 = False) | 0 |
Approvals:
| Date | Agency | Company | Orphan |
|---|---|---|---|
| None | FDA |
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| CHEBI has role | CHEBI:35718 | antifungal agent |
| CHEBI has role | CHEBI:73336 | vulnerary |
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
None
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
| Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
|---|---|---|---|---|---|---|---|---|---|
| Neuronal acetylcholine receptor subunit alpha-7 | Ion channel | IC50 | 5.51 | CHEMBL | |||||
| Signal transducer and activator of transcription 3 | Transcription factor | IC50 | 4.14 | CHEMBL |
External reference:
| ID | Source |
|---|---|
| 4020600 | VUID |
| N0000179054 | NUI |
| 4020600 | VANDF |
| CHEBI:125 | CHEBI |
| CHEMBL1096927 | ChEMBL_ID |
| CHEMBL1561544 | ChEMBL_ID |
| C056251 | MESH_SUPPLEMENTAL_RECORD_UI |
| 3667 | INN_ID |
| DB13153 | DRUGBANK_ID |
| 24WE03BX2T | UNII |
| 19461 | RXNORM |
| 006445 | NDDF |
| 010315 | NDDF |
| 768492006 | SNOMEDCT_US |
| C0053774 | UMLSCUI |
| 442343 | PUBCHEM_CID |
| C004497 | MESH_SUPPLEMENTAL_RECORD_UI |
| 24WE03BX2T | INXIGHT DRUGS |
Pharmaceutical products:
| Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
|---|---|---|---|---|---|---|---|---|
| Seamoms Tamanu Oil Mist | HUMAN OTC DRUG LABEL | 2 | 70889-920 | OIL | 0.50 g | TOPICAL | unapproved drug other | 9 sections |
| PurpleU BAOBAB FACE | HUMAN OTC DRUG LABEL | 1 | 71732-020 | OIL | 0.07 g | TOPICAL | unapproved drug other | 8 sections |
| GZE Skincare Oil | HUMAN OTC DRUG LABEL | 1 | 74458-155 | OIL | 0.50 g | TOPICAL | OTC Monograph Drug | 11 sections |
| Anubis Barcelona | HUMAN OTC DRUG LABEL | 27 | 83021-617 | CONCENTRATE | 0.00 g | TOPICAL | OTC monograph final | 9 sections |
| Anubis Barcelona Regul OIl | HUMAN OTC DRUG LABEL | 27 | 83021-624 | CONCENTRATE | 0.01 g | TOPICAL | OTC monograph final | 9 sections |
| PEGO Eczema Care Cream | HUMAN OTC DRUG LABEL | 6 | 84509-012 | CREAM | 90 mg | TOPICAL | OTC Monograph Drug | 12 sections |
| PEGO Eczema Care Cream | HUMAN OTC DRUG LABEL | 6 | 84509-041 | CREAM | 300 mg | TOPICAL | OTC Monograph Drug | 12 sections |